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Another pharmaceutical company is coming under fire for boosting the price of one of its drugs. Two lawmakers are demanding to know the justification for a more than $80,000 price hike for a year's supply of a drug that treats leukemia patients.

As NPR's Alison Kodjak reports:

"The drug is called Iclusig and it was approved in 2012 to treat a subset of patients with chronic myeloid leukemia.

Tesla has begun equipping all its new cars with self-driving hardware. Elon Musk, Tesla's CEO, tweeted Wednesday night that the new Tesla drives itself with no human input, using eight cameras, 12 ultrasonars, and radar. All this hardware is mounted so the technology is not visible to drivers.

A state district judge in Montana is facing a call for his impeachment after sentencing a man who admitted to raping his 12-year-old daughter to 60 days in jail, of which he will serve 43.

A petition posted on the website calling for the impeachment of the Valley County, Mont., district court judge, John McKeon, has more than 55,000 signatures. The petition states, "Judge McKeon did not uphold the responsibility of ensuring justice as he is required to in his elected position."

Spain's top court reversed a ban on bullfighting in the Catalonia region, saying it was unconstitutional and infringed on the government's responsibility to preserve Spain's cultural patrimony.

Catalan lawmakers approved the ban in 2010, citing animal cruelty. As NPR reported at the time, it was seen as a victory for animal rights activists and a "stinging anti-Spanish rebuke," from the fiercely independent region.

The Environmental Protection Agency had the authority and information to issue an emergency order protecting residents of Flint, Mich., from lead-tainted water a full seven months before it did so, an EPA internal investigation has concluded.

"It is clear that EPA intervention was delayed," the report from the EPA's inspector general states. "These situations should generate a greater sense of urgency."

The remains of two gigantic dinosaurs discovered in Australia may shed light on how dinosaurs spread across the globe.

The public may soon get its first glimpse at the former National Security Agency contractor who allegedly embarked on a 20-year campaign to take home national security secrets, an effort the Justice Department calls "breathtaking in its longevity and scale."

The Schiaparelli Mars lander got very close to the red planet before something went wrong. It entered the planet's atmosphere, managed not to burn up as it hurtled down and unfurled its parachute. It's unclear what happened in the final minute of descent, but it wasn't what the European and Russian space agencies had planned.

After weeks of anti-U.S. rhetoric that included denunciations of President Obama, Philippine President Rodrigo Duterte has announced "I have separated from them," using his remarks during a state visit to China to seek closer ties with that country.

The British government announced Wednesday that it intends to posthumously pardon thousands of men convicted for consensual sexual relationships with other men.

A proposed amendment dubbed the "Turing Law" was announced by the U.K.'s Ministry of Justice in a press release that said it would "build on the case of Enigma codebreaker Alan Turing, who committed suicide following his conviction for gross indecency."

Snakes used to wander the Earth on legs about 150 million years ago, before they shifted from strut to slither.

Now, two scientists have pinpointed the genetic process that caused snakes to lose their legs. What's more, they say the "molecular machinery" for leg development still persists in snakes after these millions of years — it's simply switched off.

Dorothy's ruby slippers could use a little more magic these days — or at least some preservationist TLC.

The famous shoes from The Wizard of Oz are among the most popular items on display at the Smithsonian's National Museum of American History. But they're showing their age, and the museum is asking the public to pitch in to help keep the shoes intact for decades to come.

Giant panda Bao Bao, born at the National Zoo in Washington, D.C., in August 2013, will be heading to China this winter.

Bao Bao's parents, Mei Xiang and Tian Tian, are on loan from China, and the agreement calls for any pandas born to the breeding pair to be sent to the Chinese breeding program before they turn 4.

The final presidential debate was fast-moving with candidates clashing. Trump made waves early with a racially loaded sentence on immigration. "We have some bad hombres here," he said. "And we're going to get them out." Trump defended Russia's Putin and Syria's Assad and suggested he may not accept the results of the election. Much like the first debate, Clinton was on the offense, attacking Trump on his treatment of women and his temperament. She contrasted their records: While she was in the Situation Room getting bin Laden, Trump, she said, was on Celebrity Apprentice.

A federal jury in Los Angeles found New York Knicks guard Derrick Rose not liable Wednesday in a civil suit that accused him and two friends of rape. Ryan Allen and Randall Hampton, the two friends, were also cleared.

California Attorney General Kamala Harris has launched an investigation into allegations that Wells Fargo & Co. engaged in criminal identity theft when the bank created millions of accounts without customer consent, according to the Los Angeles Times.

The Pentagon says two Americans were shot and killed in Afghanistan on Wednesday, and at least two others were wounded. One of those who died was a service member, the other was a civilian.

NPR's Tom Bowman reported the assailant opened fire at the entrance to an ammunition depot near Camp Morehead, a training center for Afghan commandos. The camp is about an hour's drive south of Kabul.

As Tom reported for our Newscast unit:

Regulators in Malaysia are trying to make something clear to food consumers: Hot dogs do not have dog meat in them.

According to The Associated Press, the Malaysian Islamic Development Department, a religious regulatory authority, has asked the U.S. company to change the name of its popular "pretzel dog" frankfurter wrapped in pretzel bread in order to obtain official halal certification.

Faculty members at more than a dozen Pennsylvania public universities went on strike on Wednesday. The Association of Pennsylvania State College and University Faculties represents educators at 14 public universities. The strike comes after negotiations broke down between the union and Pennsylvania's State System of Higher Education.

In the aftermath of the Great Depression, the U.S. government set out to evaluate the riskiness of mortgages — and left behind a stunning portrait of the racism and discrimination that has shaped American housing policy.

Now a new digital tool makes it easier than ever to see that history in high-resolution.

A powerful super typhoon pounded the coast of the Philippines late Wednesday, and aid groups say they are preparing for possible wide-scale damage.

Super Typhoon Haima unleashed maximum sustained winds of 140 mph, with gusts reaching up to 195 mph. It made landfall at about 11 p.m. local time on Wednesday in Peñablanca, in the northern tip of the country, according to the Philippine Atmospheric, Geophysical and Astronomical Services Administration.

A stone tool found in the sand has always been considered the handiwork of early humans and their ancestors. But a remarkable discovery in a Brazilian forest suggests that might not be so.

Scientists saw a group of capuchin monkeys making stone flakes, an important type of early tool. It's not clear the monkeys knew what they were making, but nonetheless, it might prompt researchers to be more cautious when they come across ancient sites where similar tools are usually attributed to early humans.

A cease-fire brokered by the United Nations took hold in Yemen on Wednesday night. The U.N. hopes the break will allow humanitarian workers to deliver badly needed aid and pave the way for peace talks.

U.N. Special Envoy for Yemen Ismail Ould Cheikh Ahmed announced the deal on Monday. A statement from the U.N. said Ahmed "has received assurances from all Yemeni parties" that they will abide by the Cessation of Hostilities that he negotiated in April.

Closing arguments are underway in the trial of seven people accused of illegally occupying Oregon's Malheur National Wildlife Refuge last year.

Saudi Arabia has raised more than $17 billion in its first foray into the global bond markets, according to news reports, as the kingdom struggles to close a budget deficit caused by declining oil prices.

The sale is the largest-ever bond offering by an emerging-market country, topping Argentina's $16.5 billion offering in August.

"Saudi's multi-part debt offering drew heavy investor demand as the world's top oil exporter sought to borrow at historic low yields," Reuters reported.

After a seven-month voyage through space and a three-day cruise to approach Mars, the European Space Agency's Schiaparelli lander is getting ready for the final leg of its journey: a six-minute trip through the red planet's atmosphere.

It's the make-it-or-crash-land-it moment for the probe, which is designed to collect data on Mars' atmosphere and dust storms. If it succeeds, it would be Europe's first successful Mars landing.

Schiaparelli was expected to enter the atmosphere at 10:42 a.m. ET on Wednesday, and make its landing at 10:48.

Outside the U.S. Embassy in Manila, a protest against the U.S. military presence in the Philippines ended with a violent police crackdown, including a police van ramming into protesters.

Police also used tear gas against the crowds and arrested dozens of protesters, according to NPR's Anthony Kuhn.

The Associated Press reports that several demonstrators were taken to the hospital after they were struck by a police van — reportedly driven by a Philippine police officer — that rammed into the protest:

Many travelers have resigned themselves to paying $25 or more to check a bag when flying. But that fee becomes especially onerous when the bag doesn't show up on the carousel at baggage claim.

The White House is proposing a new rule that would require airlines to refund the checked baggage fee if luggage is "substantially delayed," though it does not define "substantially."